JDRF Funded Research

JDRF-Funded Research: Search Results

Tomasz Heyduk ,Ph.D.

Project Title:   New methodologies for real time assessment of beta-cell function   Institution:   St. Louis University     1402 S. Grand Blvd   St. Louis   MO   USA Project duration:   01-APR-2007   to   31-MAR-2009 File No:   5-2007-347

Zhiguang Guo ,M.D., Ph.D.

Project Title:   Role of DPP-IV Inhibition in Human Beta Cell Replication   Institution:   University of Minnesota - Twin Cities   MMC 195   420 Delaware Street SE   Minneapolis   MN   USA Project duration:   01-SEP-2008   to   31-AUG-2009 File No:   26-2008-874

Peter In't Veld ,PhD,

Project Title:   Beta cell replication in human donor pancreas.   Institution:   Vrije Universiteit Brussel     Laarbeeklaan 103   Brussels,     BEL Project duration:   01-DEC-2008   to   30-NOV-2010 File No:   26-2008-896

Catherine May ,Ph.D.

Project Title:   Isl-1 Regulation of Pancreas Development and Function   Institution:   The Children's Hospital of Philadelphia   Abramson Research Center (CHOP)   3615 Civic Center Blvd Room 516E   Philadelphia   PA   USA Project duration:   01-SEP-2007   to   31-AUG-2012 File No:   2-2007-730

C. Garrison Fathman ,M.D.

Project Title:   Gene Therapy and Imaging Studies of NOD IDDM   Institution:   Stanford University   CCSR Building, Room 2225   2nd Floor   Stanford   CA   USA Project duration:   01-APR-2001   to   31-MAR-2002 File No:   5-2001-39

Jay Brenman ,Ph.D.

Project Title:   A Genetic Model to Identify Biomarkers/Targets for Diabetes Complications   Institution:   The University of North Carolina at Chapel Hill   CB 7250   105 Mason Farm Road   Chapel Hill   NC   USA Project duration:   01-AUG-2006   to   13-DEC-2007 File No:   5-2006-954

Xian Li ,MD. PhD.

Project Title:   Memory T cells in resistance to islet allograft tolerance   Institution:   Beth Israel Deaconess Medical Center, Harvard Medical School   Harvard Institute of Medicine, Rm 1025   77 Louis Pasteur Avenue   Boston   MA   USA Project duration:   01-SEP-2006   to   31-AUG-2009 File No:   1-2006-659

Ashok Singh ,Ph.D.

Project Title:   Paracrine Interactions in diabetic Nephropathy   Institution:   Hektoen Institute for Medical Research   627 South Wood Street, Suite 201     Chicago   IL   USA Project duration:   01-JAN-2000   to   31-DEC-2001 File No:   1-2000-241

Giuseppe Diaferia ,Ph.D.

Project Title:   Role of beta-1 integrins in islet cell development and function   Institution:   University of California, San Diego   9894 Genesee Avenue     La Jolla   CA   USA Project duration:   01-FEB-2004   to   31-JAN-2006 File No:   3-2004-60

Linda Lester ,MS, M.D.

Project Title:   Ex Vivo Differentiation of Primate ES Cells   Institution:   Oregon Health Sciences University   3181 SW Sam Jackson Park Road   L-607   Portland   OR   USA Project duration:   01-MAR-2003   to   31-MAR-2005 File No:   1-2003-330

Jean Lawrence ,M.P.H., M.S.S.A., Sc. D.

Project Title:   Kaiser Artificial Pancreas Project Grant   Institution:   Kaiser Permanente Southern California   Department of Research and Evaluation   100 S. Los Robles, 2nd floor   Pasadena   CA   USA Project duration:   01-DEC-2006   to   30-NOV-2008 File No:   22-2006-1125

Alberto Hayek ,M.D.

Project Title:   Modeling Pancreas from Human Embryonic Stem Cells   Institution:   The Regents of the University of California, San Diego   0983   UCSD Whittier Institute 9894 Genesee Ave, #225   La Jolla   CA   USA Project duration:   01-SEP-2008   to   31-AUG-2011 File No:   35-2008-622

William Kennedy ,M.D.

Project Title:   Sensory Nerve Regeneration Through Dermal-epidermal Basement Membrane   Institution:   University of Minnesota     420 Delaware Street S.E., Box 187 Mayo   Minneapolis   MN   USA Project duration:   01-APR-2000   to   31-MAR-2004 File No:   1-2000-318

Martha Campbell-Thompson ,Ph.D., DVM

Project Title:   Organ Processing and Pathology Core   Institution:   University of Florida   P.O. Box 115500   219 Grinter Hall   Gainesville   FL   USA Project duration:   01-DEC-2006   to   30-NOV-2009 File No:   6-2006-1140

Leroy E. (Lee) Hood ,M.D., Ph.D.

Project Title:   Bridge Support for Systems Biology of the Beta Cell   Institution:   Institute for Systems Biology   Research Administration   1441 North 34th Street   Seattle   WA   USA Project duration:   01-NOV-2007   to   31-JUL-2008 File No:   4-2008-376

Clyde R. Guidry ,Ph.D.

Project Title:   Molecular Mechanisms of Miller Cell Adhesion   Institution:   University of Alabama at Birmingham   Department of Opthalmology   Eye Foundation Hospital, DB106   Birmingham   AL   USA Project duration:   01-APR-2001   to   31-MAR-2004 File No:   1-2001-164

Bernhard Hering ,M.D.

Project Title:   "The Islet Sanctuary"   Institution:   University of Minnesota-Twin Cities   Medical School Division, Dept. of Surgery   420 Delaware Street   Minneapolis   MN   USA Project duration:   01-NOV-2005   to   30-APR-2007 File No:   7-2005-1167

Andrew Mellor ,Ph.D.

Project Title:   Creating local suppressive inflammation to block T1D progression   Institution:   Medical College of Georgia Research Institute, Inc.   1120   15th St   Augusta   GA   USA Project duration:   01-SEP-2008   to   31-AUG-2011 File No:   24-2008-945

Brian Fife ,Ph.D.

Project Title:   Antigen-specific Tolerance and Immunoregulation of Autoimmune Diabetes   Institution:   University of Minnesota Medical School   420 Delaware St. SE   MMC 108   Minneapolis   MN   USA Project duration:   01-SEP-2006   to   31-AUG-2009 File No:   10-2006-799

Hirotaka Watada ,M.D., Ph.D.

Project Title:   Regulation of beta-cell Differentiation Factor Nkx2.2 by Alternative Promoters   Institution:   University of California, San Francisco   Hormone Research Institute   Box 0534   San Francisco   CA   USA Project duration:   01-MAR-2001   to   31-MAR-2002 File No:   10-2001-255

Yi-Guang Chen ,Ph.D.

Project Title:   NKT/Dendritic Cell Interactions in Type 1 Diabetes   Institution:   Jackson Laboratory   600 Main Street     Bar Harbor   ME   USA Project duration:   01-AUG-2003   to   31-JUL-2005 File No:   3-2003-532

Bruce Riser ,Ph.D.

Project Title:   Regulation and Function of Connective Tissue Growth Factor in Diabetic Glomerulosclerosis: A Possible Therapeutic Target   Institution:   Finch University of Health Sciences/Chicago Medical School   Baxter Healthcare   1620 Waukegan Rd. MPGR-A2   McGaw   IL   USA Project duration:   01-MAR-2001   to   28-FEB-2006 File No:   1-2001-380

Fang-Xu Jiang ,Ph.D.

Project Title:   Bone morphogenetic proteins and islet beta-cell development   Institution:   Walter and Eliza Hall Institute of Medical Research   Post Office: The Royal Melbourne Hospital     Parkville, Victoria     AUS Project duration:   01-JAN-2001   to   31-DEC-2002 File No:   3-2001-232

Mark Dunne ,Ph.D.

Project Title:   Human B-cell Lines for Diabetes   Institution:   Sheffield University   Department of Biomedical Science   Western Bank   Sheffield     UK Project duration:   01-MAR-2000   to   28-FEB-2004 File No:   1-2000-133

Ronald G. Crystal ,M.D.

Project Title:   The JDRF Center for Gene Therapy and Islet Transplantation for Type 1 Diabetes at Weill Cornell .   Institution:   Weill Medical College of Cornell University   1300 York Avenue     New York   NY   USA Project duration:   01-AUG-2001   to   31-JUL-2003 File No:   4-2001-924

Leif Jansson ,PhD

Project Title:   Blood flow and islet endocrine function   Institution:   Department of Medical Cell Biology Uppsala University     Husargatan 3. Box 571   Uppsala,     SWE Project duration:   01-MAR-2005   to   28-FEB-2006 File No:   5-2005-286

Jeffrey Bluestone ,Ph.D.

Project Title:   JDRF Center for Islet Transplantation at University of California, San Francisco/University of Minnesota   Institution:   University of Chicago   5841 S. Maryland Ave.   MC2115   Chicago   IL   USA Project duration:   01-SEP-1999   to   31-AUG-2004 File No:   4-1999-841

Benjamin Geiger ,Ph.D

Project Title:   Identification of novel targets for Beta cells replacement therapy   Institution:   Weizmann Institute   1, Hertzel Street     Rehovot     ISR Project duration:   01-FEB-2007   to   31-AUG-2008 File No:   9-2007-474

Nicole Suciu-Foca ,Ph.D.

Project Title:   Induction of Tolerance to Pancreatic Islets in Hu-NOD/SCID Mice Using sILT3   Institution:   The Trustees of Columbia University in the City of New York   Box 15   630 West 168 Street - P&S 14-401   New York   NY   USA Project duration:   01-OCT-2006   to   31-AUG-2007 File No:   5-2006-957

Victoria Prince ,Ph.D.

Project Title:   Zebrafish as a physiological model of beta cell function and regeneration   Institution:   The University of Chicago   Anatomy Building   1027 E 57th St   Chicago   IL   USA Project duration:   01-SEP-2007   to   31-AUG-2009 File No:   5-2007-970

Patrik Rorsman ,Ph.D.

Project Title:   Hematopoietic Stem Cell Transplantation and Reconstruction of Insulin-Secreting Beta Cells in a Murine Model of Human Type 1 Diabetes   Institution:   Lund University   Departments of Molecular and Cellular Physiology and Stem Cell Biology   The Biomedical Centre F11, SE-221 84   Lund     SWE Project duration:   01-MAR-2002   to   28-FEB-2003 File No:   5-2002-302

Gregory S. Korbutt ,Ph.D.

Project Title:   Co-Encapsulation of Islets with Immunoprotective Sertoli Cells   Institution:   University of Alberta   Surgical-Medical Research Institute   1074 Dentistry/Pharmacy Centre   Edmonton, Alberta     CAN Project duration:   01-OCT-2000   to   30-SEP-2005 File No:   2-2000-882

Roman Hovorka ,PhD

Project Title:   Closing the loop in children and adolescents   Institution:   The University of Cambridge   Research Services Division   16 Mill Lane   Cambridge     UK Project duration:   01-OCT-2006   to   30-SEP-2008 File No:   22-2006-1113

Frederick Epstein ,Ph.D.

Project Title:   Cellular MRI for mouse models of diabetes   Institution:   The Rector and Visitors of the University of Virginia     PO Box 801339 409 Lane Road   Charlottesville   VA   USA Project duration:   01-APR-2008   to   31-MAR-2009 File No:   5-2008-293

Leonard C. Harrison ,Ph.D.

Project Title:   Generating beta cells from adult pancreas stem cells   Institution:   The Walter & Eliza Hall, Institute of Medical Research (Victoria, Australia)           AUS Project duration:   01-SEP-2007   to   17-NOV-2008 File No:   5-2007-1041

Hans Hohmeier ,Ph.D.

Project Title:   Creation and Characterization of Human Cell Lines for the Cell-based Delivery of Insulin to Patients with IDDM   Institution:   BetaGene, Inc.   2600 N. Stemmons Freeway, Suite 210     Dallas   TX   USA Project duration:   01-NOV-1999   to   31-JUL-2001 File No:   4-1999-789

Morris White ,Ph.D.

Project Title:   New molecular entities that increase IRS2 signaling in human islets   Institution:   Children's Hospital Boston   Harvard Medical School   300 Longwood Ave   Boston   MA   USA Project duration:   01-MAR-2005   to   28-FEB-2007 File No:   1-2005-839

Stephanie Amiel ,F.R.C.P.

Project Title:   Central mechanisms of glucose metabolism: brain activation by hypoglycemia and glucose ingestion in humans   Institution:   King's College London   NMSB, GKT School of Medicine, King's College Denmark Hill   Bessemer Road   London,     UK Project duration:   01-AUG-2003   to   31-JUL-2004 File No:   5-2003-663

Helen E. Thomas ,BSc(Hons), Ph.D.

Project Title:   Protection of Pancreatic Beta-cells from Apoptosis Induced by Cytotoxic T Lymphocytes   Institution:   St. Vincent's Institute   41 Victoria Parade     Fitzroy, Victoria     AUS Project duration:   01-JUL-2001   to   31-MAR-2006 File No:   10-2001-592

David Breault ,M.D., Ph.D.

Project Title:   Identification of Adult Stem Cells in Pancreas Using mTert-GFP Mice   Institution:   Children's Hospital Boston   Karp Family Research Laboratories, 4th Floor   One Blackfan Circle   Boston   MA   USA Project duration:   01-JUL-2005   to   13-DEC-2007 File No:   5-2005-216

Ashok Gowda ,B.E., M.S., Ph.D.

Project Title:   Development of an Interstitial Fluid Transcutaneous Access Port for Blood Glucose Measurement   Institution:   BioTex, Inc   1511 S. Texas Avenue     College Station   TX   USA Project duration:   01-JUL-1999   to   31-DEC-2004 File No:   4-1999-803

Stuart Williams ,B.A., M.S., Ph.D.

Project Title:   Prevascularized Immuno-Isolation Device   Institution:   Arizona Board of Regents, University of Arizona   245084   1501 N. Campbell Ave.   Tucson   AZ   USA Project duration:   01-OCT-2005   to   30-SEP-2007 File No:   5-2005-1288

Melanie Cobb ,Ph.D.

Project Title:   MAP Kinases and Glucose-regulated Islet Function   Institution:   U.T. Southwestern Medical Center at Dallas   Dept. of Pharmacology   5323 Harry Hines Boulevard   Dallas   TX   USA Project duration:   01-SEP-1999   to   31-DEC-2004 File No:   1-1999-505

Stanny Berghs ,Ph.D.

Project Title:   Role of BIV-spectrin in the Pancreatic B-cells   Institution:   Yale University School of Medicine   Dept. of Internal Medicine, Section Endocrinology, TMP 516   330 Cedar Street   New Haven   CT   USA Project duration:   01-FEB-2000   to   08-JAN-2001 File No:   3-2000-165

Lei Liu ,Ph.D.

Project Title:   Degraded Texture Discrimination Test for Early Detection of Diabetic Retinopathy   Institution:   Lighthouse International   111 east 59th Street     New York   NY   USA Project duration:   01-JUL-2001   to   30-NOV-2002 File No:   5-2001-619

Derek van der Kooy ,Ph.D.

Project Title:   Pancreatic Stem Cells   Institution:   University of Toronto     Centre for Cellular and Biomolecular Research 160 College Street - Room 1102   Toronto,Ontario,     CAN Project duration:   01-MAR-2008   to   28-FEB-2011 File No:   1-2008-23

Aubrey James Tingle ,M.D., Ph.D.

Project Title:   Major Pathway and Target Determinants of Human B-cell Damage Mediated by CTLs from IDDM Patients   Institution:   University of British Columbia   B.C. Research Institute for Children's & Women's Health   950 West 28th Avenue, Room 3084   Vancouver, B.C.     CAN Project duration:   01-APR-2000   to   31-MAR-2002 File No:   1-2000-169

Frans C. Schuit ,M.D., Ph.D.

Project Title:   Search for Important Gene Products of the Differentiated Beta-cell Phenotype   Institution:   Katholieke Universiteit Leuven   Gene Expression Unit, Afdeling Biochemie   Herestraat 49   Leuven     BEL Project duration:   01-OCT-2002   to   30-SEP-2005 File No:   1-2002-801

Guy Rutter ,Ph.D.

Project Title:   Molecular Mechanisms of Glucose Sensing by Pancreatic Islet Alpha-Cells   Institution:   University of Bristol   Henry Wellcome Signalling Laboratories and Department of Biochemistry   School of Medical Sciences, University Walk   Bristol     UK Project duration:   01-FEB-2003   to   31-JAN-2006 File No:   1-2003-235

Qing-Sheng Mi ,M.D., Ph.D.

Project Title:   MicroRNAs and diabetes susceptibility in NOD mice   Institution:   Medical College of Georgia Research Institute, Inc.   Medical College of Georgia   1120 15th Street, CA4124   Augusta   GA   USA Project duration:   01-JUN-2006   to   31-MAY-2008 File No:   5-2006-403

Claudia Menzaghi ,Ph.D.

Project Title:   Search for Insulin Resistance Genes in Juvenile Diabetes   Institution:   Joslin Diabetes Center   Harvard Medical School   One Joslin Place   Boston   MA   USA Project duration:   01-JUN-1999   to   31-DEC-2004 File No:   3-1999-369

Rubina Heptulla ,M.D.

Project Title:   The Role of Amylin and Glucagon in the Management of Normalizing Glucose Excursions in Children with Type 1 Diabetes   Institution:   Baylor College of Medicine   One Baylor Plaza     Houston   TX   USA Project duration:   01-NOV-2003   to   31-JUL-2005 File No:   1-2003-652

Vincenzo Cirulli ,M.D., Ph.D.

Project Title:   Role of Netrins and their receptors in the developing pancreas   Institution:   University of California, San Diego   9894 Genesee Avenue, Suite 221   Pediatrics   La Jolla   CA   USA Project duration:   01-MAR-2004   to   31-MAY-2008 File No:   1-2004-13

Kazuko Nishikura ,Ph.D.

Project Title:   Epigenetics of Type 1 diabetes pathogenesis   Institution:   The Wistar Institute     3601 Spruce street   Philadelphia   PA   USA Project duration:   01-APR-2006   to   31-MAR-2009 File No:   1-2006-210

Jennifer Sun ,M.D.

Project Title:   Retinal Blood Flow as a 10-Year Predictor of Diabetic Retinopathy   Institution:   Joslin Diabetes Center     One Joslin Place   Boston   MA   USA Project duration:   01-SEP-2008   to   31-AUG-2009 File No:   5-2008-732

Fraser Scott ,Ph.D.

Project Title:   SCREENING THE WHEAT PROTEOME FOR PROTEINS RELATED TO HUMAN TYPE 1 DIABETES   Institution:   Ottawa Health Research Institute   Lab N1, Box 221   501 Smyth Road   Ottawa, Ontario     CAN Project duration:   01-MAY-2004   to   30-APR-2008 File No:   1-2004-283

Chester Alper ,MD

Project Title:   Genetic and Epigenetic Studies of the MHC T1D Susceptibility Gene HLA-DQA2   Institution:   Immune Disease Institute (fka) The CBR Institute for Biomedical Research, Inc.   The CBR Institute for Biomedical Research   800 Huntington Avenue   Boston   MA   USA Project duration:   01-SEP-2008   to   31-AUG-2011 File No:   1-2008-472

Joseph S. Murray ,Ph.D.

Project Title:   Signal-1/Signal-2 Bifunctional Peptide Inhibitors of Type-1 Diabetes   Institution:   University of Kansas Center for Research   2385 Irving Hill Road     Lawrence   KS   USA Project duration:   01-JUL-2000   to   30-JUN-2001 File No:   1-2000-528

Cory Toth ,FRCPC in Neurology (Ottawa) 2002

Project Title:   NFkB and RAGE-mediated changes in the diabetic brain   Institution:   The University of Calgary   HMRB 157 Foothills Hospital   3330 Hospital Dr. NW   Calgary,Alberta,     CAN Project duration:   01-SEP-2008   to   31-AUG-2009 File No:   5-2008-708

Danny Zipris ,Ph.D.

Project Title:   Mechanisms of TLR-Induced Autoimmune Diabetes   Institution:   Reg of the Univ of Col, Univ of Col at Denv and Hlth Sci Ctr(UCDHSC)-Fitzsimons Camp     University of Colorado at Denver and Health Sciences Center, OGC F-428, PO Box 6508   Aurora   CO   USA Project duration:   01-DEC-2007   to   30-NOV-2010 File No:   1-2007-584

Yuval Dor ,Ph.D

Project Title:   Vascular signals in pancreas development and beta cell differentiation   Institution:   Institute of Medical Sciences   The Hebrew University-Hadassah Medical School   Ein Kerem   Jerusalem     ISR Project duration:   01-MAR-2007   to   31-AUG-2010 File No:   9-2007-472

Heather Harding ,Ph.D.

Project Title:   Small molecule activation of a cyto-protective stress response pathway in pancreatic islets   Institution:   New York University School of Medicine   550 First Ave, Skirball lab 3-10     New York   NY   USA Project duration:   01-MAY-2004 &